Zero-drop means the heel and forefoot sit at the same height, rather than the raised heel built into most running shoes. That changes how your foot meets the ground and lets the calf and Achilles work through their full range instead of being held in a shortened position.
The wide toe box is the other half of it: toes can spread on impact the way they would barefoot, which supports natural stability rather than relying on the shoe to provide it.
Important if you're new to minimalist shoes — transition gradually. Calves and Achilles tendons adapted to a raised heel need weeks, not days, to handle zero-drop under running load. Start with short distances and walking, and build slowly. Rushing this is the most common way people get hurt in barefoot-style shoes.
Suited to runners deliberately moving toward a minimalist stride, and to lifting where ground feel matters.